EDCs have been suspected to be associated with altered reproductive function in males and females, increased incidence of breast (BCa), testicular (TCa) and prostate cancer, abnormal growth patterns and neurodevelopmental delays in children, as well as changes in immune functions.

23% (12.6 million) of annual global deaths can be linked to the environment. Most environmental-related deaths occur in Asia, Africa and Europe.

EDCs include:

  • Traditional pollutants such as persistent organic pollutants (polychlorinated biphenyls, dioxins, hexachlorobenzene, organochlorine pesticides, perfluorooctanoic sulfonate and polybrominated diphenyl ethers)
  • Solvents (styrene, perchloroethylene, trichlorobenzene)
  • Metals (lead, cadmium, nickel, mercury and arsenic)
  • Pesticides (organochlorine and organophosphate compounds, pyrethrins and pyrethroid)
  • Plastics and their components (phthalates and bisphenol A [BPA])
  • Ingredients in cosmetic and cleaning products (parabens and triclosan)
  • Ultraviolet filters
  • Components of detergents (alkylphenols)
  • Environmental pollutants.

This is a shortened version of a CPD article created for The Specialist Forum‘s February 2020 issue. To complete a CPD about EDCs, along with the other CPD-accredited articles for this issue, go to:

https://www.medicalacademic.co.za/courses/specialist-forum-cpds-february-2020/