Psychiatric diseases are a major contributor to disability, morbidity, and mortality globally. The World Health Organisation defines mental health as ‘a state of well-being in which every individual realises his or her potential, can cope with the normal stresses of life, can work productively and fruitfully, and contribution to her or his community’. The 2019 Global Burden of Disease study, published last year, lists depressive disorders as 13th on its list of global disease burdens. This is up six places from 1990. Some of the reasons why depressive disorders are increasing are explored in our article entitled: Ticket to Happy Street. In this e-book we provide you with useful tips on how to manage patients with psychiatric disorders. Topics covered include bipolar mood disorder, major depressive disorder, pain-induced depression, seasonal depression, insomnia, post-traumatic stress disorder, phobias, obsessive compulsive disorder, seasonal anxiety disorder, and postnatal depression. In the time of Covid-19, we also take a look at the increase of psychiatric disorders as a result of social isolation and lockdown restrictions.