Rupatadine is a novel non-sedating H1-antihistamine that also has additional antagonist effects on PAF. It is a second generation antihistamine which demonstrated no adverse cardiovascular effects in clinical testing.
SPECIALIST FORUM SEPTEMBER CPD: Atopic dermatitis (eczema) is a common skin disorder characterised by a dry, itchy, inflamed skin in an age-typical distribution. Atopic dermatitis is very often the first ‘step’ in the allergic march, preceding food allergy and respiratory allergy manifestations.
Histamine is clearly not the only mediator involved in the inflammatory process. There is an emerging view that drugs that can inhibit a broader range of inflammatory agents may prove to be more effective in providing symptomatic relief in both allergic rhinitis and chronic urticaria.