Long-term PPI use: are concerns justified?

Recent studies have raised concerns about the possible adverse effects of long-term proton pump inhibitor (PPI) use, but are these really clinically significant?

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CPD POINTS: 1

Irritable bowel + irritable brain = IBS

More and more, clinical and experimental evidence is showing that IBS is a combination of an ‘irritable bowel and an irritable brain’.

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CPD POINTS: 0

7 dietary interventions in IBD

This article is based on an inflammatory bowel disease presentation by Prof Kevin Whelan of the Department of Dietetics at King’s College (United Kingdom).

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The impact of chronic stress on gut health

Gastrointestinal functioning is particularly influenced by stress. Up to 80% of IBS patients experience comorbid behavioural disorders, such as stress, anxiety or depression.

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Smoking: What should you advise your IBD patient?

This article is based on a presentation by Prof James Lindsay of the Queen Mary University of London (United Kingdom) at the recent SAGES Congress.

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The POEM procedure for achalasia: a new approach to an old therapy

Per Oral Endoscopic Myotomy or POEM is an innovative new therapy for achalasia which allows accurate surgical division of the lower oesophageal sphincter without external incisions.

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Regrowing the human oesophagus

It has been demonstrated that organogenesis is possible using principles of regenerative medicine such as transplanting tissue-engineered extracellular matrix (ECM) seeded with autologous pluripotent stem cells.

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Hepatitis C permanently damages NK cell diversity

The diversity of natural killer (NK) cells is irreversibly affected by exposure to hepatitis C, Swedish researchers claim.

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Mind over sphincter: brain-training GORD away

PPIs are not the only way to address reflux, as multiple studies into the gastrointestinal effects of relaxation training and CBT prove.

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Probiotics impact on infantile FGIDs

Many studies target probiotic therapy for conditions like colic & constipation.

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Gastroenteritis 101

Gastroenteritis is marked by inflammation of the gastrointestinal tract involving the stomach & small

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PPIs and vitamin, mineral deficiencies

The prevalence of gastro-oesophageal reflux symptoms (GORS) is on the rise. Ness-Jensen et al (2011) showed an increase in the prevalence of GORS measured over a decade. Any GORD symptoms increased by 30%, severe GORD symptoms increased by 24% and weekly GORD symptoms increased by 47%.

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CPD POINTS: 3

Not so hot

An overview of the pharmacological treatment options for gastro-oesophageal reflux (GORD) has recently been published in the South African Family Practice Journal.

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CPD POINTS: 3

Getting a grip on Gastroenteritis

Gastroenteritis is caused by common viruses and can be treated effectively with over-the-counter medication.

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CPD POINTS: 3

How effective is the LNG-IUS in relieving chronic pelvic pain caused by AM?

The definition of AM is characterised by the presence of heterotopic endometrial glands and stroma within the myometrium, >2.5mm in depth in the myometrium or more than one microscopic field at 10 times magnification from the endometrium–myometrium junction and a variable degree of adjacent myometrial hyperplasia.

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Advances in IBS

IBS also represents a major burden in terms of patient quality of life, work productivity, and healthcare costs.

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Advances in the pharmacological treatment of Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is a common functional bowel problem that mostly affects younger individuals, mostly women (a 2:1 female predominance in the western world) and patients with other functional gastrointestinal problems.

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Gut health

These are usually dealt with symptomatically with drugs that can reduce the discomfort for the patient despite the fact that this approach does not deal with the underlying problem.

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Brain-gut axis is real

IBS is defined as chronic abdominal symptoms of bloating, altered bowel habit and cramping pain arising from the colon but with no underlying organic pathology.

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CPD POINTS: 0

Advances in Irritable bowel syndrome (IBS)

Irritable bowel syndrome (IBS) is characterised by chronic intermittent abdominal pain and associated diarrhoea (IBS-D), constipation (IBS-C), or both. IBS can significantly impact patient function and quality of life.

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