This is a new review topic addressing the overall concept of atherosclerosis and where we are at this moment in time in terms of pathogenetic concepts with an emphasis on inflammation and immunity.
The first position paper on the management of patients with patent foramen ovale (PFO) and left circulation embolism explores the available trial evidence and define the principles needed to guide decision-making.
MEDICAL CHRONICLE DECEMBER 2018 CPD 3 of 3: Recently the DECLARE trial was published evaluating in a randomised, double-blind, multinational, placebo- controlled trial, the effect of Dapagliflozin on safety and efficacy for macrovascular and microvascular outcomes.
Globally the prevalence of heart failure is about one in 25 of the general population with increasing prevalence with increasing age.
As measured over the last two decades, the mortality from cardiovascular disease (CVD) has declined by about 50% and at least half of this decline has been attributed to the use of evidence-based medication.
Heart failure with reduced ejection fraction has shown improved outcomes with evidence-based treatment but heart failure with preserved ejection fraction has not shown any improved outcomes with treatment demonstrating our lack of effective therapies for this condition.