Globally, weight statistics paint an alarming picture: approximately 1.9 billion adults are overweight and 600 million are obese worldwide. In the United States alone, obesity is now the most prevalent chronic disease and obesity-related healthcare spending is estimated at $147 billion annually. This may reflect behavioural changes, particularly the easy availability and consumption of high‐calorie food, as well as an increasingly sedentary lifestyle. Within the last few decades, the increasing occurrence of obesity has led to progress towards pharmacological treatment options for weight loss. Identifying effective long-term treatment strategies for overweight and obesity is of paramount importance given the extent of the problem.

Within the last few decades, the increasing occurrence of obesity has led to progress towards pharmacological treatment options for weight loss [Image: Shutterstock].

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