BCC accounts for 75% of all skin cancers in light skinned people. Although rarer, dark skinned people are also at risk of BCC. They often present with advanced BCC and thus have poorer outcomes, according to Bradford. BCC arises mainly from the basal layer of the epidermis. Clinically, they tend to appear on sun-exposed skin. The sites most commonly affected are the head and neck region (80%) followed by the trunk (15%). The main cause of BCC is exposure to ultraviolet (UV) light, which explains why most tumours are located on sites that are mostly exposed to the sun.

Topical therapies should be considered in selected patients with low-risk superficial BCC as well as those declining surgical intervention, or if surgery is contraindicated because of patient-related factors.

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