The role of obesity in fracture risk remains uncertain and inconclusive in post-menopausal women. The aim of this study was to assess the relationship between obesity and risk of major osteoporotic fracture (MOF) after taking frailty into consideration. An MOF was considered as a clinical fracture of upper arm or shoulder, hip, spine or wrist in postmenopausal women.Led by Prof Guowei Li, based at Guangdong Second Provincial General Hospital (China) and McMaster University (Canada), the team used data from the Global Longitudinal Study of Osteoporosis in Women.

Osteoporosis is a generalised bone disease characterised by a decrease in bone mass and a deterioration of bone microarchitecture resulting in an increased risk of fracture [Image: Shutterstock].

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