Hypertension has been described as a global epidemic. Despite the expanded use of antihypertensive medication, the number of people diagnosed with the condition keeps increasing. In some countries, as many as 50% of the population older than 60 years is hypertensive. In South Africa, the prevalence is 35.1%. In 2017, the American College of Cardiology/American Heart Association’s guideline redefined the threshold for hypertension as blood pressure (BP) of 130/80mmHg on at least two occasions.

Although all classes of antihypertensive drugs have been shown to reduce the risk of CVD and stroke, studies show that those acting on the renin–angiotensin–aldosterone system (RAAS) are particularly effective.

Please sign in to read more