Cancer is caused by a combination of genetic and non-genetic changes induced by environmental factors that trigger inappropriate activation or inactivation of specific genes, leading to unregulated cell proliferation. Over the past decade, there has been an increased tendency to classify tumours from one based on histologic and anatomic characteristics to one increasingly incorporating genomic data, says Prof Rapoport.

Biomarkers are used to identify patients who are likely to benefit from a certain type of therapy.

Please sign in to read more